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As expected, these signals were sensitive to imatinib treatment only in WT-Bcr-Abl-32D cells but not T315I-Bcr-Abl-32D cells, while ponatinib 27 treatment abolished these signals in both cell lines (Supplementary Fig

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The EMT cell transcriptome is characterized by the expression of proteins with multiple functions, such as growth factors and corresponding protein factor receptors (TGF, HGF, HGFR), accessory transcription factors (Wnt, Notch, NFkB), integrin receptors, proteoglycan joint receptors CD44, and glucose-6-phosphate isomerase (GPI) (173)

doi: 10.3389/fgene.2021.790093